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Propranolol
Clinical data
Pronunciationprəʊˈpranəlɒl
Trade namesInderal, others
AHFS/Drugs.comMonograph
License dataEU  EMA:  by INN, US   FDA: Propranolol
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, rectal, intravenous
ATC codeC07AA05 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability26%
Protein binding90%
MetabolismLiver (extensive) 1A2, 2D6; minor: 2C19, 3A4
MetabolitesN-desisopropylpropranolol, 4’-hydroxypropanolol
Elimination half-life4–5 hours
ExcretionKidney (<1%)

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Although propranolol generally is less can i take propranolol with benadryl in the management of ventricular arrhythmias than supraventricular arrhythmias and is usually not the first drug of choice for ventricular arrhythmias, it may be considered when cardioversion or other drugs are not effective.Before beginning any tapering regimen, the patient must be fully stabilized; that is, all signs and symptoms of withdrawal must be improved.

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